Chiattone 2. Resposta medular inadequada. A ferritinemia encontra-se normal ou aumentada. Tais medidas devem ser consideradas caso a caso 11, 12, Abstract The anemia of chronic disease ACD is usually defined as the anemia occurring in chronic infectious, inflammatory disorders, or neoplastic diseases, and is one of the most common syndromes in the clinical practice. The three principal pathologic mechanisms involved in ACD are: reduced erythrocyte survival, bone marrow failure to increase red blood cell production to compensate for the increase in its demand, and abnormal mobilization of reticuloendothelial iron stores.
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