GLYCEMIC DURABILITY OF ROSIGLITAZONE METFORMIN OR GLYBURIDE MONOTHERAPY PDF

The efficacy of thiazolidinediones, as compared with other oral glucose-lowering medications, in maintaining long-term glycemic control in type 2 diabetes is not known. We evaluated rosiglitazone, metformin, and glyburide as initial treatment for recently diagnosed type 2 diabetes in a double-blind, randomized, controlled clinical trial involving patients. The patients were treated for a median of 4. The primary outcome was the time to monotherapy failure, which was defined as a confirmed level of fasting plasma glucose of more than mg per deciliter Prespecified secondary outcomes were levels of fasting plasma glucose and glycated hemoglobin, insulin sensitivity, and beta-cell function. The difference in the durability of the treatment effect was greater between rosiglitazone and glyburide than between rosiglitazone and met

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The efficacy of thiazolidinediones, as compared with other oral glucose-lowering medications, in maintaining long-term glycemic control in type 2 diabetes is not known. We evaluated rosiglitazone, metformin, and glyburide as initial treatment for recently diagnosed type 2 diabetes in a double-blind, randomized, controlled clinical trial involving patients.

The patients were treated for a median of 4. The primary outcome was the time to monotherapy failure, which was defined as a confirmed level of fasting plasma glucose of more than mg per deciliter Prespecified secondary outcomes were levels of fasting plasma glucose and glycated hemoglobin, insulin sensitivity, and beta-cell function.

The difference in the durability of the treatment effect was greater between rosiglitazone and glyburide than between rosiglitazone and met Continue Reading.

This feed focuses on the association of cardiovascular diseases in patients with type 2 diabetes. Antipsychotic-induced weight gain aiwg is a common adverse effect of this treatment, particularly with second-generation antipsychotics, and it is a major health problem around the world.

Here are the latest discoveries pertaining to AIWG. How it Works Discover Feeds. Dec 6, Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy The New England Journal of Medicine. Get PDF. References 27 Citations Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes UKPDS Intensive insulin therapy prevents the progression of diabetic microvascular complications in Japanese patients with non-insulin-dependent diabetes mellitus: a randomized prospective 6-year study opens in new tab.

Diabetes Research and Clinical Practice. Y Ohkubo M Shichiri. Overview of 6 years' therapy of type II diabetes: a progressive disease. Prospective Diabetes Study Group opens in new tab. Beta-cell function is a major contributor to oral glucose tolerance in high-risk relatives of four ethnic groups in the U.

S opens in new tab. See more references from this paper Sign Up. Diabetes Care. Chantal Mathieu Nayyar Iqbal. Management of diabetic complications: a chemical constituents based approach opens in new tab. Journal of Ethnopharmacology. Randhir Singh Girish Kumar Gupta. Linong Ji Satish K Garg. The scientific evidence: vildagliptin and the benefits of islet enhancement opens in new tab.

Chantal Mathieu. Effect of once weekly dulaglutide by baseline beta-cell function in people with type 2 diabetes in the AWARD programme opens in new tab. See more citations of this paper Sign Up. Mentioned in this Paper. Diabetes Mellitus, Non-Insulin-Dependent. Insulin Sensitivity. Hemoglobin, Glycosylated. Kaplan-Meier Estimate. Thiazolidinediones, blood glucose lowering drugs. Plasma Fasting Glucose Measurement.

Cardiovascular Diseases. About this Paper. PMID: DOI: Related Feeds. Antipsychotic-Induced Weight Gain Antipsychotic-induced weight gain aiwg is a common adverse effect of this treatment, particularly with second-generation antipsychotics, and it is a major health problem around the world.

Related Papers. Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes opens in new tab. The New England Journal of Medicine. Steven Nissen , Kathy Wolski. Effect of rosiglitazone on the frequency of diabetes in patients with impaired glucose tolerance or impaired fasting glucose: a randomised controlled trial opens in new tab. Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes UKPDS

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Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy.

Either your web browser doesn't support Javascript or it is currently turned off. In the latter case, please turn on Javascript support in your web browser and reload this page. Read article at publisher's site DOI : Prospective Diabetes Study Group. Yki-Jarvinen H.

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Glycemic Durability of Rosiglitazone, Metformin, or Glyburide Monotherapy

METHODS: We evaluated rosiglitazone, metformin, and glyburide as initial treatment for recently diagnosed type 2 diabetes in a double-blind, randomized, controlled clinical trial involving patients. The patients were treated for a median of 4. The primary outcome was the time to monotherapy failure, w Queue ["Typeset",MathJax. The file s for this record are currently under an embargo. If you complete the attached form, we can attempt to contact the author and ask if they are willing to let us send you a copy for your personal research use only. We will then pass this form and your request on to the author and let you know their response.

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Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy

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