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Buccal mucosal urethroplasty for balanitis xerotica obliterans related urethral strictures: the outcome of 1 and 2-stage techniques. Balanitis xerotica obliterans BXO related strictures are complex and generally managed by 2-staged urethroplasty.
We present our results with 1-stage dorsal onlay and 2-stage buccal mucosal urethroplasty for such strictures. Between January and April , 39 patients underwent buccal mucosal urethroplasty for BXO related anterior urethral strictures. The 25 patients with a salvageable urethral plate group 1 were treated with 1-stage dorsal onlay urethroplasty using a cosmetic incision. The 14 patients with a severely scarred urethral plate, focally dense segments or active infection group 2 underwent 2-stage urethroplasty.
Outcomes in terms of cosmetic appearance, stricture recurrence and complications in the 2 groups were assessed. At a mean followup of All patients had a normal slit-like meatus and none had chordee or erectile dysfunction.
Four group 2 patients Following stage 2, 3 patients had recurrent stricture, of whom 2 were treated with optical urethrotomy and 1 underwent repeat urethroplasty. In BXO related strictures with a viable urethral plate 1-stage dorsal onlay buccal mucosal urethroplasty provides excellent intermediate term results. The cosmetic incision described provides a normal, wide caliber, slit-like glans.
Two-stage procedures provide satisfactory outcomes but they are associated with a higher revision rate. Directory of Open Access Journals Sweden. Full Text Available Balanitis xerotica obliterans BXO is a chronic inflammatory skin disorder, considered the male genital variant of lichen sclerosus. Anti-inflammatory drugs are commonly used in BXO. To analyse the incidence of BXO among paediatric circumcisions for preputial pathology, in particular in children under the age of 5 years.
Retrospective review revealed paediatric circumcisions performed between and at our institution. Data were collected on patient's age, date when sample received by pathology department and histological findings for all the foreskin samples received and examined during the study period. A total of foreskin samples were received and BXO was found in There were 31 children under the age of 5 years circumcised for preputial pathology.
BXO was reported in 6 The foreskin was reported normal in 2 6. Epidemiological population data analysis revealed the incidence of BXO per year to be 3. The incidence of BXO in boys noted in our study is higher than previously reported. BXO can result in significant complications and should be considered in children even under 5 years.
Published by Elsevier Ltd. All rights reserved. Bronchiolitis Obliterans. It irritates the skin, eyes, mucous membranes, A rare case of preputial calculi in a child with balanitis xerotica Jul 26, The patient had not been Continuous urine What can you tell me about cryptogenic organizing pneumonia? Answers from Teng Moua, M. Previously called bronchiolitis obliterans with organizing pneumonia, cryptogenic organizing pneumonia COP is a rare lung Cerebral angiographic findings in thromboangiitis obliterans.
However, there has been debate regarding the mechanism of ischemic stroke in TAO. An angiogram showed multiple alternative areas of arterial occlusions in the distal segments of both middle cerebral arteries. Extensive collateral vessels around the occluded segment were also observed, which resembled the ''tree root'' or ''corkscrew'' vessels described in the peripheral arteries in TAO. Our patient illustrates that cerebral manifestations of TAO may occur with vascular changes that are identical with those encountered in the limb arteries in TAO.
Thromboangiitis obliterans Buerger's disease is a vasculitis with undulating clinical course multisegmentarily affecting small and medium-sized arteries and veins. The disease is closely linked to tobacco-use. Increasing knowledge of autoimmunologic mechanisms in the complex pathophyiology of the disease let to the formulation of an autoimmunity-hypothesis now serving as a new paradigma. New treatment options comprise progenitor-cell-therapy, immunoadsorption, use of sendothelin-receptor-blocking agent Bosentan, and prescriptions of antiphosphodiesterase-V-inhibitors.
Bronchiolitis obliterans organising pneumonia in patients taking acebutolol or amiodarone. Two patients, treated with acebutolol and amiodarone respectively, developed a disease clinically, radiologically, and pathologically indistinguishable from bronchiolitis obliterans organising pneumonia.
In one case recovery followed discontinuation of acebutolol; in the other case cessation of amiodarone had no effect, and corticosteroids were required. In addition to these patients, several cases of bronchiolitis obliterans organising pneumonia have been reported during treatment with gold salts, amiodarone, and miscellaneous other drugs. Taken together, this information supports the view that bronchiolitis obliterans organising pneumonia may be a form of response by the lungs to insult by drugs.
Images PMID Full Text Available Introduction. Bortezomib is a proteasome inhibitor indicated for the treatment of multiple myeloma patients. The most frequent side effects are gastrointestinal and neurological. Serious pulmonary complications have been described rarely. This case involves a year-old man suffering from IgG Kappa myeloma treated with bortezomib, melphalan, and dexamethasone.
After administering chemotherapy, the patient developed an acute respiratory distress syndrome ARDS. A surgical pulmonary biopsy proved the existence of bronchiolitis obliterans organizing pneumonia BOOP lesions.
This is the first reported histologically confirmed case of bortezomid-induced BOOP. Faced with severe respiratory symptoms in the absence of other etiologies, complications due to bortezomid treatment should be evoked and corticotherapy considered. Full Text Available Bronchiolitis obliterans organizing pneumonia due to nitrofurantoin has rarely been reported and is associated with poor outcomes.
A case of nitrofurantoin-associated bronchiolitis obliterans organizing pneumonia responsive to drug withdrawal and corticosteroids is presented. Full Text Available Rituximab-induced lung disease R-ILD is a rare entity that should be considered in patients treated with rituximab who present with dyspnea, fever, and cough, but no clear evidence of infection.
A variety of pathologic findings have been described in this setting. Bronchiolitis obliterans organizing pneumonia BOOP is the most common clinicopathologic diagnosis, followed by interstitial pneumonitis, acute respiratory distress syndrome ARDS, and hypersensitivity pneumonitis. Prompt diagnosis and treatment with corticosteroids are essential as discussed by Wagner et al. Here we present a case of an year-old man who was treated with rituximab for recurrent marginal zone lymphoma.
After the first infusion of rituximab, he reported fever, chills, and dyspnea. On computed tomography imaging, he was found to have bilateral patchy infiltrates, consistent with BOOP on biopsy. In our patient, BOOP was caused by single-agent rituximab, in the first week after the first infusion of rituximab. We reviewed the relevant literature to clarify the different presentations and characteristics of R-ILD and raise awareness of this relatively overlooked entity. Full Text Available Bronchiolitis obliterans syndrome BOS, the main manifestation of chronic lung allograft dysfunction, leads to poor long-term survival after lung transplantation.
Identifying predictors of BOS is essential to prevent the progression of dysfunction before irreversible damage occurs. An independent set from 25 lung recipients was used for validation by quantitative PCR 13 stables, 11 in the prediction group, and 8 in the diagnosis group.
We identified 50 transcripts differentially expressed between stable and BOS recipients. This condition usually manifests in middle-aged or elderly uncircumcised men. Although of unknown etiology, different factors have been reported to be involved in its genesis local infections, poor hygiene, heat, friction, and constant rubbing. It is generally considered to be a benign condition, and its association with malignancies has been rarely reported.
Bronchiolitis obliterans in children with Stevens-Johnson syndrome: follow-up with high resolution CT.
About one third of children with Stevens-Johnson syndrome have pulmonary involvement. As a consequence of airway epithelial injury, bronchiolitis obliterans can occur in these patients. Two cases of Stevens-Johnson syndrome-associated bronchiolitis obliterans in children were diagnosed and followed by high resolution CT without open lung biopsy. Serial changes of high resolution CT features of bronchiolitis obliterans are discussed and the literature is reviewed.
Clinical and radiological features of bronchiolitis obliterans in children. Objective: To study the value of chest radiograph and thin-section computed tomography CT in diagnosis bronchiolitis obliterans in children, and to determine clinical view of obliterative bronchiolitis in children.
Methods: We identified 12 infants, 10 boys, and 2 girls age range, 5 month to 11 years with clinical confirmation of bronchiolitis obliterans. Three cases were after Steven-Johnson syndrome, 8 were post-infection 2 adenovirus, 2 measles and 1 Pseudomonas aeruginosa infection, 3 cases were unknown etiology infection ; The symptoms lasted for at least 6 weeks. One case had lung ventilation nuclear scan. We evaluated individual bronchoscopy, pulmonary function test, chest radiograph and thin- section CT features and their characteristic appearance.
Results: All cases had typical clinical characteristics and pulmonary function testing results that were consistent with nonreversible small airways obstruction.
One case had lung ventilation nuclear scan illustrated absent and reduced ventilation of the right lower lobe. Nine cases who underwent bronchoscopy were chronic endobronchial inflammation.
Three children had transbronchial biopsy and 1 patient who underwent open pulmonary biopsies were uncertain of histological diagnosis.
Conclusions: In our study, correct diagnoses of bronchiolitis obliterans in children were made more special with thin-section CT than with chest radiographs. The diagnosis of BO in. Quinine-induced bronchiolitis obliterans and organizing pneumonia. Full Text Available Quinine is a vital anti-malarial drug used in the management of resistant Falciparum malaria.
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Cellulitis is a bacterial infection involving the inner layers of the skin. The legs and face are the most common sites involved, though cellulitis can occur on any part of the body. Treatment is typically with antibiotics taken by mouth, such as cephalexin , amoxicillin or cloxacillin. Potential complications include abscess formation. The typical signs and symptoms of cellulitis is an area which is red, hot, and painful. The photos shown here are of mild to moderate cases, and are not representative of earlier stages of the condition.
Buccal mucosal urethroplasty for balanitis xerotica obliterans related urethral strictures: the outcome of 1 and 2-stage techniques. Balanitis xerotica obliterans BXO related strictures are complex and generally managed by 2-staged urethroplasty. We present our results with 1-stage dorsal onlay and 2-stage buccal mucosal urethroplasty for such strictures. Between January and April , 39 patients underwent buccal mucosal urethroplasty for BXO related anterior urethral strictures.